✦ LIBER ✦
Studies on a chinese hamster line that is temperature sensitive for the commitment to DNA synthesis
✍ Scribed by B. J. Smith; N. M. Wigglesworth
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 470 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The Chinese hamster cell line K12 is temperature sensitive for the initiation of DNA synthesis and for the programming of rounding up to enter mitosis. Viability is lost expontentially after twelve hours at the non‐permissive temperature. This temperature sensitivity is reversed following exposure of K12 cells to SV40 virus.