Physiologic surface-active agents and drug absorption VIII: Effect of bile flow on sulfadiazine absorption in the rat
β Scribed by Charles H. Nightingale; James E. Axelson; Milo Gibaldi
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 377 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Modern drug discovery chemical libraries contain a large number of molecular entities exhibiting low aqueous solubility, often necessitating the inclusion of solubilizing agents in preclinical models of absorption or metabolism. The objective of the present study was to investigate the effects of se
The influence of preadministration of phenobarbital, benzo[alpha]pyrene, and proadifen hydrochloride on 3-O-methylglucose transfer across the everted rat small intestine was examined. The active and passive components of the sugar transport mechanism were evaluated using phlorizin, a potent inhibito