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Physicochemical properties of recombinant hepatitis B surface antigen expressed in mammalian cell (C127)

✍ Scribed by Young Soo Lee; Byong Kak Kim; Eung-Chil Choi


Publisher
Springer
Year
1998
Tongue
English
Weight
867 KB
Volume
21
Category
Article
ISSN
0253-6269

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The human hepatoblastoma-derived cell line HB6 I I secretes hepatitis-B surface antigen (HBsAg) and hepatitis-B e antigen (HBeAg) into the medium. Hepatitis-B-virus(HBV) DNA integrated into the cellular genome was found to be hypermethylated. When the cells were treated with 5-azacytidine for 3 days