✦ LIBER ✦

Physico-chemical properties of hyaluronan and its hydrophobic derivatives: a calorimetric and viscometric study

✍ Scribed by Renata Geciova; Antonella Flaibani; Franco Delben; Gianfranco Liut; Ranieri Urbani; Attilio Cesáro

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 745 KB
Volume: 196
Category: Article
ISSN: 1022-1352
DOI: 10.1002/macp.1995.021960914

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The physico‐chemical properties of a series of hyaluronan derivatives were studied with the aim of exploring some aspects of the role of electrostatic interactions on the aggregation of these chains in aqueous solution. Experimental data were obtained from calorimetric measurements of the dilution process in water. The data were analysed in terms of the structural charge parameter, ζ, with the polyelectrolyte counterion condensation theory. In addition, intrinsic viscosity data of the hyaluronan derivatives were obtained at several different values of the ionic strength and discussed on the basis of the effect of charge density change upon the elongation properties of the polyelectrolyte chains.

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