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Physical mapping of the human T-cell receptor beta gene complex, using yeast artificial chromosomes

✍ Scribed by Yasmeen Hashim; Ioannis Ragoussis; Lyndal Kearney; Sabrina Tosi; Alex K. So


Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
578 KB
Volume
41
Category
Article
ISSN
0093-7711

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In order to increase the rate of generation of a contiguous human chromosome 19 physical map, we have investigated the advantages of using a bacterial artificial chromosome (BAC) library in comparison with other systems. This cloning system, recently described, can faithfully propagate DNA fragments