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Physical Map of Mouse Chromosome 17 in the Region Relevant for Positional Cloning of the Hybrid sterility 1 Gene

✍ Scribed by Zdenek Trachtulec; Vladimir Vincek; Renata M.J. Hamvas; Jiri Forejt; Hans Lehrach; Jan Klein


Book ID
115612321
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
427 KB
Volume
23
Category
Article
ISSN
0888-7543

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## Abstract Duplicon‐mediated microdeletions around the __NF1__ gene are frequently associated with a severe form of neurofibromatosis type I in a subgroup of patients who show an earlier onset of cutaneous neurofibromas, dysmorphic facial features, and lower IQ values. To clarify the discrepancies