𝔖 Bobbio Scriptorium
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Physical basis of a protein-DNA recognition code

✍ Scribed by Yen Choo; Aaron Klug


Book ID
117656124
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
826 KB
Volume
7
Category
Article
ISSN
0959-440X

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We present a fast method for finding optimal parameters for a low-resolution (threading) force field intended to distinguish correct from incorrect folds for a given protein sequence. In contrast to other methods, the parameterization uses information from >10(7) misfolded structures as well as a se