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Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer

✍ Scribed by Liu, Ying; Emilion, Gracy; Mungall, Andrew J; Dunham, Ian; Beck, Stephan; Le Meuth-Metzinger, Valerie G; Shelling, Andrew N; Charnock, Francis ML; Ganesan, Trivadi S


Book ID
110066289
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
811 KB
Volume
21
Category
Article
ISSN
0950-9232

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Chromosome 6 has been shown to contain at band q27 a minimal region of deletion associated with epithelial ovarian cancers and AF6, a gene disrupted in acute myeloid leukemia with t(6;l l)(q27;q23). Using rapid amplification of cDNA ends by polymerase chain reaction, the breakpoint in AF6 was confir