We studied the physical and biophysical affects of the nonionic surfactants polysorbate 20 and 80 and their mechanism of interaction using darbepoetin alfa, a 4-helix bundle protein, as the exemplary protein. Differences were observed between the abilities of the polysorbates to prevent surface loss
Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa
โ Scribed by Deechongkit, Songpon (author);Wen, Jie (author);Narhi, Linda O. (author);Jiang, Yijia (author);Park, Sungae S. (author);Kim, Justin (author);Kerwin, Bruce A. (author)
- Publisher
- John Wiley and Sons Inc.
- Year
- 2009
- Tongue
- English
- Weight
- 358 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0022-3549
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