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Phylogenetic analysis of hepatitis B virus full-length genomes reveals evidence for a large nosocomial outbreak in Belgium

✍ Scribed by Mahmoud Reza Pourkarim; Jannick Verbeeck; Mustafizur Rahman; Samad Amini-Bavil-Olyaee; An-Marie Forier; Philippe Lemey; Piet Maes; Marc Van Ranst

Book ID
116631655
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
662 KB
Volume
46
Category
Article
ISSN
1386-6532

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## Abstract In hepatitis B virus (HBV)‐endemic countries, the majority of hepatocellular carcinoma (HCC) arises in HBV carriers. High frequency of mutations at nucleotides 1762(Aβ†’T) and 1764(Gβ†’A) in the core promoter region have been described in HCC. Due to the differences in genetic backgrounds,