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PHOTOSENSITIZATION OF SINGLE-STRAND BREAKS IN pBR322 DNA BY ROSE BENGAL

✍ Scribed by THOMAS A. CIULLA; JOHN R. VAN CAMP; EVAN ROSENFELD; IRENE E. KOCHEVAR


Book ID
114895560
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
601 KB
Volume
49
Category
Article
ISSN
0031-8655

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Flavonoids, the dominant colouring pigments of plants, as well as the related polyphenol tannic acid significantly inhibit single-strand breaks in plasmid pBR322 DNA induced by singlet molecular oxygen ((1)O2). This reactive species of oxygen was generated in an aqueous buffer system by the thermal