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Singlet oxygen induced single-strand breaks in plasmid pBR322 DNA: the enhancing effect of thiols

✍ Scribed by Thomas P.A. Devasagayam; Paolo Di Mascio; Stephan Kaiser; Helmut Sies

Book ID
119120070
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
270 KB
Volume
1088
Category
Article
ISSN
0167-4781

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Protection of plasmid pBR322 DNA by flav
Protection of plasmid pBR322 DNA by flavonoids against single-strand breaks induced by singlet molecular oxygen
✍ Thomas P.A. Devasagayam; Mayilvahanan Subramanian; B.B. Singh; R. Ramanathan; Na πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 672 KB

Flavonoids, the dominant colouring pigments of plants, as well as the related polyphenol tannic acid significantly inhibit single-strand breaks in plasmid pBR322 DNA induced by singlet molecular oxygen ((1)O2). This reactive species of oxygen was generated in an aqueous buffer system by the thermal