Photophysical studies of phenosafranin interaction with phospholipids in liposomes

✍ Scribed by Chirasree Sen-Varma; Benoy B. Bhowmik

• Publisher: Elsevier Science
• Year: 1990
• Tongue: English
• Weight: 549 KB
• Volume: 56
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(90)90091-5

✦ Synopsis

Spectrophotometric studies show that phenosafranin (PSF), a cationic phenazine dye forms 1:1 molecular complexes with phosphatidylcholine (PC), lysoPC and Ca-salt of phosphorylcholine chloride 0aCC) in sonicated aqueous dispersion and the site of interaction in PC has been identified. The same systems generate photovoltage when studied in a photoelectrochemical cell and the mechanism of photo-voltage generation supports this interaction which is charge-transfer (CT) or electron donor acceptor (EDA) in nature between the dye as an electron acceptor and PC and its components as electron donors The electrode kinetics of photoinduced electron transfer reaction have also been studied. Results indicate that the mode of lipid organization plays a significant role in the interaction. A good correlation has been found among the photovoltage generation of the systems, spectral shifts due to complex formation and thermodynamic properties of these complexes.