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Photon correlation spectroscopy as a probe of planar lipid bilayer phase transitions

✍ Scribed by G. E. Crawford; J. C. Earnshaw

Publisher
Springer
Year
1984
Tongue
English
Weight
852 KB
Volume
11
Category
Article
ISSN
1432-1017

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✦ Synopsis

Photon correlation spectroscopy has been applied to study phase transitions of planar bilayer membranes. The membrane tension and one specific membrane viscosity are probed. Difficulties arising in the measurement of the temperature dependence of these properties are discussed and a servo-control system to overcome them is described. Typical data are presented for monoglyceride bilayers. Membranes incorporating cholesterol display effects below the lipid transition temperature which are interpreted in terms of separation within the membrane into cholesterol-rich fluid regions and regions of lipid in the gel phase. Some of the cholesterol-rich regions are apparently of macroscopic extent.

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