Photometric determination of some aromatic aldehydes with barbituric acid and of barbituric acid with p-dimethylaminobenzaldehyde
β Scribed by Ali Mohammad; H. S. Rathore; M. Qureshi
- Book ID
- 112338050
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 265 KB
- Volume
- 292
- Category
- Article
- ISSN
- 1618-2650
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π SIMILAR VOLUMES
## Abstract Several aromatic and Ξ±,Ξ²βconjugated aromatic aldehydes were condensed with barbituric acid in methanol solution in the absence of acid or base as a catalyst, affording 5βylidenebarbituric acid derivatives in almost quantitative yields.
A very inexpensive, simple, and high yield procedure for the preparation of valuable pharmaceutical intermediates, 5-cyclohexylmethylbarbiturates, was developed starting from either p-hydroxy or p-methoxybenzaldehyde and barbituric acid. Although the reaction sequence involves several steps, such as