Diphenyl disulphide, 4,4'diaminodiphenyl disulphide, 2,2'diaminodiphenyl disulphide, 4,4'dimethyldiphenyl disulphide and 4,4'dinitrodiphenyl disulphide, when administered orally to rats, induced haematological and pathological changes indicative of erythrocyte destruction in vivo. No evidence of hae
Photolysis of aromatic disulphides
โ Scribed by Y. Schaafsma; A.F. Bickel; E.C. Kooyman
- Publisher
- Elsevier Science
- Year
- 1960
- Tongue
- French
- Weight
- 282 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4020
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๐ SIMILAR VOLUMES
Diphenyl disulphide has been shown to generate hydrogen peroxide in erythrocytes in vitro. It also induces oxidative damage (reversible and irreversible haemoglobin oxidation, depletion of non-protein and proteinbound thiols) in these cells. Such changes were also recorded in erythrocytes exposed t
The aromatic thiol, thiophenol, is readily autoxidized at neutral pH in a reaction which generates superoxide radical and hydrogen peroxide. The oxidation product, diphenyl disulphide, may be reduced back to thiophenol by glutathione and in the presence of an excess of the latter thiol a reduction/a