Multi-detachable resin supports for soli
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James P. Tam; Foe S. Tjoeng; R.B. Merrifield
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Article
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1979
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Elsevier Science
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French
โ 255 KB
Two multi-detachable resin supports, each containing orthogonally removable benzyl and photolabile esters were prepared and applied to the synthesis of Leu-enkephalin and angiotensin. These resins, called Pop and Pon, could be cleaved by acid to give the free peptide, by nucleophiles to give protect