The synthesis, material characterization, and in vitro biocompatibility of S-nitrosothiol (RSNO)-modified xerogels are described. Thiol-functionalized xerogel films were formed by hydrolysis and co-condensation of 3-mercaptopropyltrimethoxysilane (MPTMS) and methyltrimethoxysilane (MTMOS) sol-gel pr
β¦ LIBER β¦
Photoinitiated Nitric Oxide-Releasing Tertiary S -Nitrosothiol-Modified Xerogels
β Scribed by Riccio, Daniel A.; Coneski, Peter N.; Nichols, Scott P.; Broadnax, Angela D.; Schoenfisch, Mark H.
- Book ID
- 120484653
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 892 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1944-8244
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## Abstract A new type of nitric oxide (NO)βreleasing material is described that utilizes __S__βnitrosothiols anchored to tiny fumed silica (FS) particles as the NO donor system. The synthetic procedures suitable for tethering three different thiol species (cysteine, __N__βacetylcysteine, and __N__