Photodynamic therapy of experimental colonic tumours with 5-aminolevulinic-acid-induced endogenous porphyrins
✍ Scribed by K. Orth; K. König; F. Genze; A. Rück
- Book ID
- 112502506
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 403 KB
- Volume
- 120
- Category
- Article
- ISSN
- 1432-1335
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Photodynamic therapy and photodynamic diagnosis help to support efficient treatment of superficial and early-stage cancer. During the last few years, 5-aminolevulinic acid (5-ALA), a precursor of haemoglobin in the haem biosynthetic pathway, was used to stimulate endogenous porphyrin production. In
## Background and Objective: The impact of photodynamic therapy (PDT) on the endometrium following topical application of 5-aminolevulinic acid (ALA) was studied in a rat model. Study Design/ Materials and Methods: Fluorescence microscopy revealed peak ALA to protoporphyrin IX (Pp IX) conversion 3