Photocyclization of 1-(2-Halophenyl)-3,4-dihydro-6,7-dimethoxyisoquinolines: A Short and New Synthesis of Triclisine.
β Scribed by M. M. V. Ramana; R. H. Sharma; J. A. Parihar
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 16 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
In a previous paper') we described the generation of o-lithiomethylphenyl isocyanide, which was a versatile reagent for syntheses of indole derivatives. Herein, we wish to report an elaboration of the lithiomethylphenyl isocyanide to lead to heterocycles such as 4,5-dihydro-3,1-benzoxazepine ~~ and
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The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines