Synthesis and Functionalization of 6,7-Dihydro-[1,4]dioxino[2,3-d]pyrimidines.
✍ Scribed by Guido Lavecchia; Sabine Berteina-Raboin; Gerald Guillaumet
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 22 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract magnified image The condensation of 5‐amino‐4‐phenyl‐1,2,3‐triazole (**1**) with chalcones **2a‐e** or 3‐dimethylamino‐propiophenone (**4f**) leads to the 6,7‐dihydro‐(1,2,3)‐triazolo[1,5‐__a__]pyrimidines **3a‐f.** The equilibrium of **3** and the tautomeric 4,7‐dihydro‐(1,2,3)‐triazo
## Abstract A general synthetic approach to pyrazolo[4,3‐__d__]pyrimidines is reported. Aldehydes, arylideneanilines, carboxylic acids and orthoesters are used as one‐carbon units for bridging the two amino functions of 4‐amino‐1‐alkyl‐3‐propylpyrazole‐5‐carboxamides.