Mutagenicity detection of in vivo nitros
โ
Whong, Wen-Zong ;Speciner, Norman D. ;Edwards, Gordon S.
๐
Article
๐
1979
๐
Wiley (John Wiley & Sons)
โ 326 KB
In vivo nitrosation of dimethylamine by nitrite was measured with an intrahepatic host-mediated mutagenicity assay using Salmonella typhimurium as the detecting organism. It was possible to detect the product, N-nitrosodimethylamine, at much lower doses with this system than with previously reported