Photoaffinity ligands for the MU opioid receptor
β Scribed by Eric J. Simon; Li-Qun Fan; Jacob M. Hiller; Ahmad Seyed-Mozaffari; Arthur G. Schultz; Sydney Archer
- Book ID
- 118346312
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 267 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0024-3205
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Background: The aim of the present study was to describe the activity of a set of opioid drugs, including partial agonists, in a cell system expressing only mu opioid receptors. receptor activation was assessed by measuring the inhibition of forskolin-stimulated cyclic adenosine mono phosphate (
Opiate receptors play major roles in analgesic and euphoric effects of opiate drugs. Recent cloning of cDNAs encoding the rodent and human p receptor revealed high homology between the predicted receptors but also some sequence differences. To determine if these sequence differences produced signifi