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New scaffolds in the development of Mu opioid-receptor ligands

✍ Scribed by Daniel Pagé; Natalie Nguyen; Sylvain Bernard; Martin Coupal; Mylène Gosselin; Julie Lepage; Lynda Adam; William Brown

Book ID
108477461
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
198 KB
Volume
13
Category
Article
ISSN
0960-894X

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## Background: The aim of the present study was to describe the activity of a set of opioid drugs, including partial agonists, in a cell system expressing only mu opioid receptors. receptor activation was assessed by measuring the inhibition of forskolin-stimulated cyclic adenosine mono phosphate (