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Photoactivation of an Inhibitor of the 12/15-Lipoxygenase Pathway

✍ Scribed by Stephan Herre; Torsten Schadendorf; Igor Ivanov; Christian Herrberger; Wencke Steinle; Karola Rück-Braun; Robert Preissner; Hartmut Kuhn


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
316 KB
Volume
7
Category
Article
ISSN
1439-4227

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Disruption of the 12/15-lipoxygenase gen
✍ Marcos Martínez-Clemente; Natàlia Ferré; Esther Titos; Raquel Horrillo; Ana Gonz 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 849 KB

We have shown that Alox15, the gene encoding for 12/15-lipoxygenase (12/15-LO), is markedly up-regulated in livers from apolipoprotein E-deficient (ApoE 2/2 ) mice, which spontaneously develop nonalcoholic fatty liver disease secondary to hyperlipidemia. In the current study, we used ApoE 2/2 mice w