Intestinal motor patterns are not well developed in premature infants. Similarly, in neonatal mice, irregular motor patterns were observed. Pacemaker cells, identified in the small intestine as interstitial cells of Cajal (ICCs) associated with Auerbach's plexus (ICC-APs), contribute to the generati
Photo-reversal of the circadian rhythm in the proliferative activity of the mouse small intestine
β Scribed by Curtis P. Sigdestad; S. Lesher
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 284 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Mice (C57Bl) were placed for 35 days in a room with reversed light cycle; lights came on at 1800 hours and off at 0600 hours. At six hour intervals throughout the day three mice were injected with tritiated thymidine and sacrificed 30 minutes later. Crypts were dissected for radioautography and determination of disintegrations per minute per crypt, the number of cells in mitosis and the number of cells synthesizing DNA was determined. The results reported clearly demonstrate reversal of the circadian rhythm in the parameters tested.
π SIMILAR VOLUMES
Mitotic activity in the duodenum of the rat and mouse exhibits a circadian periodicity with a peak in the rat between 1200 and 1500 hours and a sustained trough between 1800 and 0600. Scintillation counts revealed a similar rhythm in the total uptake of 3H-thymidine by the rat duodenum with a sustai
Background: The recent availability of antisera to the vesicular acetylcholine transporter (VAChT) and choline acetyltransferase (ChAT) that demonstrate peripheral cholinergic neurons has made possible the anatomical identification of cholinergic neurons in the enteric nervous system. In this study,