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Phosphorylation of myelin basic protein and peptides by ganglioside-stimulated protein kinase

โœ Scribed by Kai-Foon Jesse Chan


Book ID
115761628
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
679 KB
Volume
165
Category
Article
ISSN
0006-291X

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Gangliosides inhibit the phosphorylation of both small and large rat myelin basic proteins (SMBP, LMBP) by an endogenous phospholipid-sensitive Ca\*+-dependent protein kinase (C-kinase). Using a rat brain myelin preparation in an in vitro phosphorylation assay system, we determined the inhibition co