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In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein kinase

✍ Scribed by MIYAMOTO, EISHICHI; KAKIUCHI, SHIRO; KAKIMOTO, YASUO

Book ID: 109690324
Publisher: Nature Publishing Group
Year: 1974
Tongue: English
Weight: 222 KB
Volume: 249
Category: Article
ISSN: 0028-0836
DOI: 10.1038/249150a0

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Protein phosphorylation is a well-known mechanism by which extracellular molecules or factors transduce their signals into intracellular effects. In the context of myelin assembly, phosphorylation of major myelin proteins affects the electrostatic repulsion between adjacent proteins within myelin st