Phosphorylation of 1-alkylmidazoles and
โ
Andrej A. Tolmachev; Aleksandr A. Yurchenko; Anatolij S. Merculov; Marina G. Sem
๐
Article
๐
1999
๐
John Wiley and Sons
๐
English
โ 269 KB
Phosphorylation of 1-alkyl substituted imidazoles and benzimidazoles with P(III) halides in pyridine was shown to proceed at the 3-N atom of the heteroaryl ring and was followed by triethylamine-induced migration of the phosphorus group to the 2-C atom. Preparative methods were developed for the syn