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ChemInform Abstract: Phosphorylated Azoles. Part 2. Phosphorylation of 1-Alkylimidazoles and 1-Alkylbenzimidazoles with Phosphorus(III) Halides in the Presence of Bases.

โœ Scribed by Andrej A. Tolmachev; Aleksandr A. Yurchenko; Anatolij S. Merculov; Marina G. Semenova; Evgenij V. Zarudnitskii; Vladimir V. Ivanov; Aleksandr M. Pinchuk


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
31
Category
Article
ISSN
0931-7597

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Phosphorylation of 1-alkylmidazoles and
โœ Andrej A. Tolmachev; Aleksandr A. Yurchenko; Anatolij S. Merculov; Marina G. Sem ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 269 KB

Phosphorylation of 1-alkyl substituted imidazoles and benzimidazoles with P(III) halides in pyridine was shown to proceed at the 3-N atom of the heteroaryl ring and was followed by triethylamine-induced migration of the phosphorus group to the 2-C atom. Preparative methods were developed for the syn