Phosphorylation of histones in mouse mammary tumors
β Scribed by J.G. Georgatsos; G. Rammos; D. Palavradzi; A. Symeonidis
- Book ID
- 113145020
- Publisher
- Elsevier Science
- Year
- 1968
- Weight
- 316 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0014-2964
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The mouse mammary tumor virus enters mammary epithelial cells via a plasma membrane protein that binds to a viral envelope glycoprotein, gp52. In intact cells, this gp52 receptor can be phosphorylated by activators of protein kinase A and protein kinase C (PKC), but this modification does not occur
## Abstract The expression of the mouse mammary tumor virus (MMTV) in hormoneβinduced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinityβ and ionβexchange chromatography columns. The purified viral