Histone phosphorylation in explants of mouse mammary glands and tumors
✍ Scribed by M. Sluyser; O. H. J. Destrée
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 646 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0301-4851
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The mouse mammary tumor virus enters mammary epithelial cells via a plasma membrane protein that binds to a viral envelope glycoprotein, gp52. In intact cells, this gp52 receptor can be phosphorylated by activators of protein kinase A and protein kinase C (PKC), but this modification does not occur
## Abstract The expression of the mouse mammary tumor virus (MMTV) in hormone‐induced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinity‐ and ion‐exchange chromatography columns. The purified viral