Lactate dehydrogenase isozyme spectrum in mouse mammary gland tumors and metastases in the lungs
β Scribed by I. P. Tereshchenko; V. I. Boikova; I. S. Zaretskaya
- Publisher
- Springer US
- Year
- 1975
- Tongue
- English
- Weight
- 186 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0007-4888
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## Abstract ## Background Human breast cancer metastasizes mainly to lymph nodes, lungs, liver, and bone; in the majority of cases, it is the development of metastases which leads to death. In order to suppress mammary cancer metastasis, we applied __in vivo__ electrogene transfer (nonβviral metho
Extensive extraction studies with Triton X-100 revealed only LDH-1 (B4) but no trace of LDH-5 (A4) in one-cell and two-cell mouse and rat embryos. The LDH isozyme pattern of preimplantation mouse embryos changes from the maternally inherited B subunit isozyme (LDH-1) to a pattern dominated by LDH-5