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Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription

โœ Scribed by Serizawa, Hiroaki; Conaway, Joan Weliky; Conaway, Ronald C.


Book ID
109784303
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
560 KB
Volume
363
Category
Article
ISSN
0028-0836

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Cdc2 kinase triggers the entry of mammalian cells into mitosis, the only cell cycle phase in which transcription is globally repressed. We show here that Cdc2 kinase phosphorylates components of the RNA polymerase II transcription machinery including the RNA polymerase II carboxy-terminal repeat dom