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Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells

✍ Scribed by Jackson, James G; Kreisberg, Jeffrey I; Koterba, Alan P; Yee, Douglas; Brattain, Michael G

Book ID
110064140
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
209 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Human breast cancer MCF‐7 cells, growth‐arrested by serum starvation, were stimulated with recombinant human insulinlike growth factor‐1 (IGF‐I). An increase in DNA synthesis was induced 20 hr later, which was as effective as that induced by serum. The increase in DNA synthesis was sign