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Phosphorylated α-synuclein as a potential biomarker for Parkinson’s disease and related disorders

✍ Scribed by Foulds, Penelope; Mann, David MA; Allsop, David


Book ID
120452540
Publisher
Expert Reviews
Year
2012
Tongue
English
Weight
270 KB
Volume
12
Category
Article
ISSN
1473-7159

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## Abstract The effect of PAMAM dendrimers (generations G3, G4 and G5) on the fibrillation of __α__‐synuclein was examined by fluorescence and CD spectroscopy, TEM and SANS. PAMAM dendrimers inhibited fibrillation of __α__‐synuclein and this effect increased both with generation number and PAMAM co