The covalent attachment of a phospholipid moiety, bound to the 5'-ends of phosphodiester and phosphorothioate oligonucleotides (L-ODNs and LS-ODNs), was achieved using H-phosphonate chemistry, and the lipid-oligonucleotides were assayed for the inhibition of virus replication in HIV-1 infected MT-4
β¦ LIBER β¦
Phosphorothioate analogues of oligodeoxyribonucleotide: Synthesis and activity as inhibitors of replication of human immunodeficiency virus
β Scribed by Sang-Gug Kim; Yoshikazu Suzuki; Hideki Nakashima; Naoki Yamamoto; Hiroshi Takaku
- Book ID
- 115764539
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 419 KB
- Volume
- 179
- Category
- Article
- ISSN
- 0006-291X
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