Obtained in five steps from N-acetylneuraminic acid (Neu5Ac) according to known procedures [3]. Zto and Ogawa indicate a ratio 12/13 of 1:4.1 [lo]. Such a neighbouring group participation [ 121 and particularly the formation of 6,8-dioxa[3.2.l]bicyclooctane structures similar to 15 have been describ
β¦ LIBER β¦
Phosphonic-Acid Analogues of the N-Acetyl-2-deoxyneiiraniinic Acids: Synthesis and Inhibition of Vibrio cholerae Sialidase
β Scribed by Kurt Wallimann; Andrea Vasella
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- German
- Weight
- 987 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
β¦ Synopsis
ing an equatorial COOH group is a moderatly strong inhibitor of the N-acetylneuraminidases from Vibrio cholerae and fowl plague virus, whilst the epimeric acid possessing axial COOH and HO-C(4) groups is not [2].
π SIMILAR VOLUMES
Synthesis of a Phosphonic Acid Analogue
β
Andrea Vasella; RenΓ© Wyler
π
Article
π
1991
π
John Wiley and Sons
π
German
β 922 KB
N-(4-Nitrophenyl)oxamic Acid and Related
β
Markus Engstler; Roland Schauer; Miguel A. Ferrero-GarcΓa; Armando J. Parodi; Th
π
Article
π
1994
π
John Wiley and Sons
π
German
β 486 KB
Structural Variations on N-acetylneurami
β
Schreiner, Erwin ;Zbiral, Erich ;Kleineidam, Reinhard G. ;Schauer, Roland
π
Article
π
1991
π
John Wiley and Sons
π
English
β 652 KB
## Abstract The peracetylated methyl ester 1 of Nβacetylneuraminic acid was transformed into the oxazoline derivative 2, which was hydrogenated with Pd/C/H~2~ to give the 4βdeoxyβNeu5Ac2en derivative 3. Acid cleavage of the oxazoline 2 by trifluoroacetic acid (THF) gave the 4βepiβNeu5Ac2en derivati
Carbocyclic Analogues of N-Acetyl-2,3-di
β
Steffen Vorwerk; Andrea Vasella
π
Article
π
1998
π
John Wiley and Sons
π
English
β 119 KB
π 1 views
Structural Variations ofN-Acetylneuramin
β
Zbiral, Erich ;Schreiner, Erwin ;Christian, Rudolf ;Kleineidam, Reinhard G. ;Sch
π
Article
π
1989
π
John Wiley and Sons
π
English
β 763 KB
ChemInform Abstract: Carbocyclic Analogu
β
S. VORWERK; A. VASELLA
π
Article
π
2010
π
John Wiley and Sons
β 28 KB
π 1 views