๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Structural Variations ofN-Acetylneuraminic Acid, 10. Synthesis of 2,7-, 2,8-, and 2,9-Dideoxy- and 2,4,7-Trideoxy-2,3-didehydro-N-acetylneuraminic Acids and Their Behavior Towards Sialidase fromVibrio cholerae

โœ Scribed by Zbiral, Erich ;Schreiner, Erwin ;Christian, Rudolf ;Kleineidam, Reinhard G. ;Schauer, Roland


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
763 KB
Volume
1989
Category
Article
ISSN
0947-3440

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Structural Variations ofN-Acetylneuramin
โœ Zbiral, Erich ;Brandstetter, Hannelore H. ;Christian, Rudolf ;Schauere, Roland ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English

Thl: perawtylstcd mcthyl cstcr dcrivativcs of 7-rpi-i-NeuSAc (ta), H-epi-NeuSAc (3 a), and 7.8-bis-epi-NcuSAc (4 a) wcrc transformed hy trimcihylsilyl trifluoromethanesulronale into the corrcsponding 2-cieoxy-2,3-didehydro derivatives 2b-4 b. As minor products the 4.5-osazolino derivatives 5 b rind

Structural Variations ofN-Acetylneuramin
Structural variations ofN-acetylneuramin
โœ Schreiner, Erwin ;Christian, Rudolf ;Zbiral, Erich ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 545 KB

## Abstract The methyl ester of __N__โ€acetylneuraminic acid ฮฒโ€methyl ketoside (Neu5Ac1Meโ€2ฮฒโ€Me) (1) is used as common starting material for the synthesis of the title compounds. Combined derivatization reactions with reagents thiophosgene, __p__โ€cresol, benzoyl chloride, and acetic anhydride/pyridi

Structural Variations on N-acetylneurami
โœ Schreiner, Erwin ;Zbiral, Erich ;Kleineidam, Reinhard G. ;Schauer, Roland ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 652 KB

## Abstract The peracetylated methyl ester 1 of Nโ€acetylneuraminic acid was transformed into the oxazoline derivative 2, which was hydrogenated with Pd/C/H~2~ to give the 4โ€deoxyโ€Neu5Ac2en derivative 3. Acid cleavage of the oxazoline 2 by trifluoroacetic acid (THF) gave the 4โ€epiโ€Neu5Ac2en derivati