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Phospholipid studies of marine organisms. 7. Stereospecific synthesis of (5Z,9Z)-, (5Z,9E)-, (5E,9Z)-, and (5E,9E)-5,9-hexacosadienoic acid

✍ Scribed by Mena, Philippe L.; Pilet, Olivier; Djerassi, Carl


Book ID
126202428
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
693 KB
Volume
49
Category
Article
ISSN
0022-3263

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3Z,6E)-l-Bromododeca-3,6-diene, a common intermediate in the synthesis of labelled 12t linoleic acid and 14t arachidonic acid, was obtained from (E)-3-nonyl-l-ol, in four steps, via conventional functional manipulations. Cross-coupling of this bromododecadiene with the Grignard reagent of l-chloro-5