NMR structure of phospho-tyrosine signal
β
Carol Beth Post; Beverly S. Gaul; Elan Zohar Eisenmesser; Michael L. Schneider
π
Article
π
1999
π
John Wiley and Sons
π
English
β 213 KB
A structural basis for activation and substrate specificity of src tyrosine kinases, and regulation of protein-protein association by tyrosine phosphorylation is described. Lyn, a src-family tyrosine kinase, recognizes and phosphorylates the immunoreceptor tyrosine-based activation motif, ITAM, a cr