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Phosphine-Catalyzed Domino Reactions: A Route to Functionalized Bicyclic Skeletons

✍ Scribed by Li, Erqing; Huang, You


Book ID
121714242
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
320 KB
Volume
20
Category
Article
ISSN
0947-6539

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AbstractÐAn ef®cient synthesis of pharmaceutically interesting amphetamines by a base-catalyzed domino-isomerization±hydroamination reaction is presented. Starting from allylbenzene and various primary or secondary amines, the basic structural pattern of amphetamines is synthesized directly in yield