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Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca2+-activated secretion

✍ Scribed by Hay, Jesse C.; Martin, Thomas F. J.


Book ID
109787128
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
424 KB
Volume
366
Category
Article
ISSN
0028-0836

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## Abstract Calcium (Ca) ionophores trigger cortical granule exocytosis in progesterone‐matured Xenopus oocytes (eggs), but not in immature oocytes. Prior work suggested that this secretory transition involved a Ca‐dependent isoform of protein kinase C (PKC). To address this possibility, we treated