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ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

✍ Scribed by Hay, Jesse C.; Fisette, Phillip L; Jenkins, Glenn H; Fukami, Kiyoko; Takenawa, Tadaomi; Anderson, Richard A.; Martin, Thomas F. J.

Book ID
109791372
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
545 KB
Volume
374
Category
Article
ISSN
0028-0836

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## Abstract Calcium (Ca) ionophores trigger cortical granule exocytosis in progesterone‐matured Xenopus oocytes (eggs), but not in immature oocytes. Prior work suggested that this secretory transition involved a Ca‐dependent isoform of protein kinase C (PKC). To address this possibility, we treated