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Phosphate transport in ehrlich ascites tumor cells and the effect of arsenate

✍ Scribed by Charles Levinson

Publisher: John Wiley and Sons
Year: 1972
Tongue: English
Weight: 401 KB
Volume: 79
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040790108

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✦ Synopsis

The effect of extracellular Pi and arsenate on Pi-transport in Ehrlich ascites tumor cells has been studied. Pi-transport can be described by Michaelis-Menten kinetics; the maximal flux equal to 44 mmoles (kg cell water)-' hour-' and K m equal to 3.3 X 1 0 -4 M. Arsenate is a competitive inhibitor of Pi-transport with an inhibition constant ( K i ) equal to 2.41 X M.

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