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Evaluation of the mode of cell death in ehrlich ascites tumor

✍ Scribed by Peeyush K. Lala

Publisher: John Wiley and Sons
Year: 1972
Tongue: English
Weight: 460 KB
Volume: 29
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197201)29:1<261::aid-cncr2820290139>3.0.co;2-z

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✦ Synopsis

Since there was a progressive transition of proliferating cells into a non-proliferating resting state, as well as an increased rate of cell loss in the aging ascites tumor, we examined whether cell loss preferentially affected the nonproliferating or the proliferating cells. The kinetics of cell loss in the 7-day ascites tumor obtained with inoculation of 108 cells was evaluated by repeated labeling with Ha-thymidine (H3TdR), combined with the measurements of cell cycle characteristics by the labeled mitosis technique after a single injection of Paper presented at the Tenth International Cancer Congress, Houston, Tex., May 22-29,lWO.

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