Phorbol esters: probes of protein kinase C function in the brain
β Scribed by Jay M. Baraban
- Book ID
- 118390411
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 263 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0166-2236
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An antibody to the mammalian protein kinase C alpha (PKCalpha) subunit and brain dissection was used for immunoblot analysis of this protein in various brain regions of Apteronotus leptorhynchus. Western blots revealed that the antibody labeled a band of the expected molecular mass (approximately 80
## Abstract The phorbol ester receptor protein kinase C (PKC) gene family encodes essential mediators of various eukaryotic cellular signals. The molecular dissection of its mechanisms of action has been limited in part by the genetic inaccessibility and complexity of signaling in mammalian cells.