## Abstract The present study has characterized several aspects of the mouse epidermal protein kinase C (PKC) system and compared phorbol esterโsensitive andโresistant mice. Protein immunoblots of partially purified epidermal PKC preparations from SENCAR and C57BL/6 mice indicated the presence of t
Phorbol ester activation of epidermal protein kinase C from tumor promotion sensitive and resistant mouse strains
โ Scribed by Garte, Seymour J.; Edinger, Francis; Mufson, R.Allan
- Book ID
- 122934538
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 459 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0304-3835
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The phosphorylation of an Mr 82,000 protein (p82) in the Triton X-100 extract of the particulate fraction of mouse epidermis is dependent on the phorbol ester 1 2-O-tetradecanoylphorbol-13-acetate (TPA) or diacylglycerol and phospholipid and, contrary to protein kinase C (PKC)-catalyzed phosphorylat