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Philadelphia-negative acute lymphoblastic leukemia in a chronic myeloid leukemia patient receiving dasatinib

✍ Scribed by Santos, Fabio P.S.; Rodrigues, Morgani; Mac-Donald Bley do Nascimento, Claudia; Kerbauy, Fábio R.; Ribeiro, Andreza Alice Feitosa; Mauro Kutner, José; Hamerschlak, Nelson


Book ID
122266183
Publisher
Informa plc
Year
2010
Tongue
English
Weight
75 KB
Volume
12
Category
Article
ISSN
1465-3249

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Unusual expression of mRNA typical of Ph
✍ Kirk, Judy A.; Radich, Jerald; Edmands, Scott; Lee, Arthur; VanDevanter, Donald 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 647 KB

The Philadelphia chromosome (Ph) is found in both chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). The Ph translocation, t(9;22)(q34;qll), can disrupt the BCR gene on chromosome 22 in one to two areas called the major (Mbcrl) and minor (mbcrl) breakpoint cluster regions. In CML