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Phenytoin modulates the pharmacokinetics of prednisolone and the pharmacodynamics of prednisolone as assessed by the inhibition of the mixed lymphocyte reaction in humans

โœ Scribed by BRIGITTE M. FREY; FELIX J. FREY

Book ID
114726350
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
575 KB
Volume
14
Category
Article
ISSN
0014-2972

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The nonlinear pharmacokinetics of predni
The nonlinear pharmacokinetics of prednisone and prednisolone. II. Plasma protein binding of prednisone and prednisolone in rabbit and human plasma
โœ Jame S. J. Ferry; John G. Wagner ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 451 KB ๐Ÿ‘ 2 views

The protein binding characteristics of prednisone and prednisolone were determined in human and rabbit plasma and in a 4.7 per cent human serum albumin (HSA) solution. The influence of plednisolone on prednisone binding in human plasma was also examined. Prednisolone exhibited nonlinear binding and